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This patient information on Diazolidinylurea is provided by John L. Meisenheimer, M.D. a board certified Dermatologist and skin care specialist based in Orlando, Florida.  This information is not intended as a substitute for the medical advice or treatment of a dermatologist or other physician.

The results from your patch testing showed a positive reaction (contact allergy) to Diazolidinylurea. Your immune system reacts with its defense mechanisms with each exposure of Diazolidinylurea to your skin. It is unknown why certain individuals develop allergic sensitivities. In some it may take repeat exposures over long periods of time before an allergy develops. Once you have become sensitized (allergic) your immune system always "remembers" and you will be Diazolidinylurea sensitive. If you currently have eczema this chemical may be the cause but other factors may play a role as well. The information below will help you avoid this allergen.

This chemical is used as a broad-spectrum antimicrobial agent and preservative, most commonly found in cosmetics and pharmaceutical preparations. This chemical is a formaldehyde releaser and may cross-react with patients sensitive to formaldehyde.

Where is chemical found?
►Cosmetic
►Creams
►Hair care products
►Lotions
►Toiletries
►Pharmaceutical preparations

Hints on avoiding chemical:
►Choose products listed only on your personalized Contact Allergen Database, which has been provided to you. Products listed on your contact allergen resource database will be free of Diazolidinylurea and safe to use.
►Please be aware that if your spouse or significant other uses topical skin care products that contain this chemical skin-to-skin transfer may occur to you.

Other names you may see this chemical listed as:
2,5-Diazolidinylurea
Germaben II
Germall II
N, N'-Bis (hydroxymethyl) urea
N- (hydroxymethyl)-N- (1,3- dihroxymethl-2, 5-dioxo-4-imidazolidinyl)-N'- (hydroxymethyl) urea

© John L. Meisenheimer, M.D.  2004                                   WWW.OrlandoSkinDoc.com

Last modified: 08/27/06